Andreas A. Werdich, Ph.D.

Andreas Werdich, PhD

Director of AI and Data Science, Core for Computational Biomedicine

Andreas Werdich is a physicist who received a Diploma in atomic physics from Freiburg University, Germany, and a PhD in physics from Vanderbilt University. His dissertation was focused on studying the molecular mechanisms of cardiac arrhythmias using high-speed fluorescence imaging of single cells in microfluidic devices. Dr. Werdich completed postdoctoral fellowships at Massachusetts General Hospital and Case Western Reserve University and in 2015, joined the faculty of Harvard Medical School at Brigham Women’s Hospital. Since then, he has been specializing in data science and computer vision, using deep learning techniques to uncover attributes of human health and disease in experimental and clinical data. As the head of the AI and Data Science team at the Core for Computational Biomedicine, Dr. Werdich enjoys helping his colleagues at Harvard Medical School to bridge the gaps between medicine, biomedical engineering and data science. He continues to work in the areas of cardiac electrophysiology and arrhythmias through collaborations with Harvard teaching hospitals.

Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channel.
Authors: Panáková D, Werdich AA, Macrae CA.
Nature
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Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.
Authors: Kikuchi K, Holdway JE, Werdich AA, Anderson RM, Fang Y, Egnaczyk GF, Evans T, Macrae CA, Stainier DY, Poss KD.
Nature
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Rapid behavior-based identification of neuroactive small molecules in the zebrafish.
Authors: Kokel D, Bryan J, Laggner C, White R, Cheung CY, Mateus R, Healey D, Kim S, Werdich AA, Haggarty SJ, Macrae CA, Shoichet B, Peterson RT.
Nat Chem Biol
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Differential effects of phospholamban and Ca2+/calmodulin-dependent kinase II on [Ca2+]i transients in cardiac myocytes at physiological stimulation frequencies.
Authors: Werdich AA, Lima EA, Dzhura I, Singh MV, Li J, Anderson ME, Baudenbacher FJ.
Am J Physiol Heart Circ Physiol
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Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice.
Authors: Werdich AA, Baudenbacher F, Dzhura I, Jeyakumar LH, Kannankeril PJ, Fleischer S, LeGrone A, Milatovic D, Aschner M, Strauss AW, Anderson ME, Exil VJ.
Am J Physiol Heart Circ Physiol
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Differential pH measurements of metabolic cellular activity in nl culture volumes using microfabricated iridium oxide electrodes.
Authors: Ges IA, Ivanov BL, Werdich AA, Baudenbacher FJ.
Biosens Bioelectron
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Thin-film IrOx pH microelectrode for microfluidic-based microsystems.
Authors: Ges IA, Ivanov BL, Schaffer DK, Lima EA, Werdich AA, Baudenbacher FJ.
Biosens Bioelectron
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A microfluidic device to confine a single cardiac myocyte in a sub-nanoliter volume on planar microelectrodes for extracellular potential recordings.
Authors: Werdich AA, Lima EA, Ivanov B, Ges I, Anderson ME, Wikswo JP, Baudenbacher FJ.
Lab Chip
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