Evan Koch

Evan Koch, PhD

Research Fellow in Biomedical Informatics

Sunyaev Lab

Publications

A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription.

Authors: Seplyarskiy V, Koch EM, Lee DJ, Lichtman JS, Luan HH, Sunyaev SR.
Nat Genet 2023-12-01
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Demographic and Viral-Genetic Analyses of COVID-19 Severity in Bahrain Identify Local Risk Factors and a Protective Effect of Polymerase Mutations.

Authors: Koch EM, Du J, Dressner M, Alwasti HE, Al Taif Z, Shehab F, Mohamed AM, Ghanem A, Alhajeri A, Alawadhi A, Almoamen N, Ashoor K, Hasan S, Haghighi A, Sunyaev S, Farhat M.
medRxiv 2023-10-12
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Recurrent mutation in the ancestry of a rare variant.

Authors: Wakeley J, Fan WL, Koch E, Sunyaev S.
Genetics 2023-07-06
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Mutation rates and adaptive variation among the clinically dominant clusters of Mycobacterium abscessus.

Authors: Commins N, Sullivan MR, McGowen K, Koch EM, Rubin EJ, Farhat M.
Proc Natl Acad Sci U S A 2023-05-30
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Population sequencing data reveal a compendium of mutational processes in the human germ line.

Authors: Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnett DK, Blangero J, Boerwinkle E, He J, Montgomery C, Rao DC, Rotter JI, Taylor KD, Brody JA, Chen YI, de Las Fuentes L, Hwu CM, Rich SS, Manichaikul AW, Mychaleckyj JC, Palmer ND, Smith JA, Kardia SLR, Peyser PA, Bielak LF, O'Connor TD, Emery LS, Gilissen C, Wong WSW, Kharchenko PV, Sunyaev S.
Science 2021-08-27
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Population-specific causal disease effect sizes in functionally important regions impacted by selection.

Authors: Shi H, Gazal S, Kanai M, Koch EM, Schoech AP, Siewert KM, Kim SS, Luo Y, Amariuta T, Huang H, Okada Y, Raychaudhuri S, Sunyaev SR, Price AL.
Nat Commun 2021-02-17
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Maintenance of Complex Trait Variation: Classic Theory and Modern Data.

Authors: Koch EM, Sunyaev SR.
Front Genet 2021-01-01
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