Kun-Hsing Yu, MD, PhD

Kun-Hsing Yu, MD, PhD

Assistant Professor of Biomedical Informatics, Harvard Medical School
Assistant Professor of Pathology, Brigham and Women's Hospital
Instructor in Epidemiology, Harvard T.H. Chan School of Public Health
Yu Lab

Kun-Hsing "Kun" Yu received his PhD in Biomedical Informatics and PhD Minor in Computer Science from Stanford University, and he obtained his MD from National Taiwan University, Taiwan. His research focuses on the integration of quantitative histopathology image patterns with multi-omics (genomics, epigenomics, transcriptomics, and proteomics) profiles to advance cancer research and clinical practice. His team has developed fully-automated algorithms to analyze whole-slide histopathology images at scale, discovered the molecular mechanisms underpinning the microscopic phenotypes of tumor cells, and identified novel cellular morphologies for patient prognosis. His research interests include quantitative pathology, machine learning, and translational bioinformatics.

DBMI Research Areas
DBMI Courses
Current Postdoctoral Fellowship Opportunities
Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks.
Authors: Yu KH, Wang F, Berry GJ, Ré C, Altman RB, Snyder M, Kohane IS.
J Am Med Inform Assoc
View full abstract on Pubmed
Examining the Use of Real-World Evidence in the Regulatory Process.
Authors: Beaulieu-Jones BK, Finlayson SG, Yuan W, Altman RB, Kohane IS, Prasad V, Yu KH.
Clin Pharmacol Ther
View full abstract on Pubmed
Autoimmune Effects of Lung Cancer Immunotherapy Revealed by Data-Driven Analysis on a Nationwide Cohort.
Authors: Yang S, Yu KH, Palmer N, Fox K, Kou SC, Kohane IS.
Clin Pharmacol Ther
View full abstract on Pubmed
Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex.
Authors: Sánchez Fernández I, Yang E, Calvachi P, Amengual-Gual M, Wu JY, Krueger D, Northrup H, Bebin ME, Sahin M, Yu KH, Peters JM.
PLoS One
View full abstract on Pubmed
Suicide Rates Among Adolescents and Young Adults in the United States, 2000-2017.
Authors: Miron O, Yu KH, Wilf-Miron R, Kohane IS.
JAMA
View full abstract on Pubmed
Evaluation of Taroni et al.: Understanding Rare Diseases by MultiPLIER.
Authors: Yu KH.
Cell Syst
View full abstract on Pubmed
Evaluation of the association of bariatric surgery with subsequent depression.
Authors: Yuan W, Yu KH, Palmer N, Stanford FC, Kohane I.
Int J Obes (Lond)
View full abstract on Pubmed
Data-driven analyses revealed the comorbidity landscape of tuberous sclerosis complex.
Authors: Yu KH, Miron O, Palmer N, Lemos DR, Fox K, Kou SC, Sahin M, Kohane IS.
Neurology
View full abstract on Pubmed
Framing the challenges of artificial intelligence in medicine.
Authors: Yu KH, Kohane IS.
BMJ Qual Saf
View full abstract on Pubmed
Artificial intelligence in healthcare.
Authors: Yu KH, Beam AL, Kohane IS.
Nat Biomed Eng
View full abstract on Pubmed