Kun-Hsing Yu, MD, PhD

Kun-Hsing Yu, MD, PhD

Assistant Professor of Biomedical Informatics, Harvard Medical School
Assistant Professor of Pathology, Brigham and Women's Hospital
Instructor in Epidemiology, Harvard T.H. Chan School of Public Health

Kun-Hsing "Kun" Yu received his PhD in Biomedical Informatics and PhD Minor in Computer Science from Stanford University, and he obtained his MD from National Taiwan University, Taiwan. His research focuses on the integration of quantitative histopathology image patterns with multi-omics (genomics, epigenomics, transcriptomics, and proteomics) profiles to advance cancer research and clinical practice. His team has developed fully-automated algorithms to analyze whole-slide histopathology images at scale, discovered the molecular mechanisms underpinning the microscopic phenotypes of tumor cells, and identified novel cellular morphologies for patient prognosis. His research interests include quantitative pathology, machine learning, and translational bioinformatics.

DBMI Research Areas
DBMI Courses
Current Postdoctoral Fellowship Opportunities
A Cloud-Based Metabolite and Chemical Prioritization System for the Biology/Disease-Driven Human Proteome Project.
Authors: Yu KH, Lee TM, Chen YJ, Ré C, Kou SC, Chiang JH, Snyder M, Kohane IS.
J Proteome Res
View full abstract on Pubmed
Education for the future.
Authors: Pietrzak B, Ward A, Cheung MK, Schwendimann BA, Mollaoglu G, Duong MT, Ulltveit-Moe N, Allareddy V, Dutton-Regester K, Zhang J, Scult MA, Naz S, Singh PC, Yan HY, Isaacson K, Dennis AF, Al-Humaidan EI, Beardsley FR, Lo C, Sood P, Jones T, Nieuwenhuis R, Ali BA, Yu KH, Arthur PK, Kumar B, Chen A, Buschke F, Cingl L, Zaidi SS, O'Mullane AP, Coetzee V, Konstantinides N.
Science
View full abstract on Pubmed
Systematic Protein Prioritization for Targeted Proteomics Studies through Literature Mining.
Authors: Yu KH, Lee TM, Wang CS, Chen YJ, Ré C, Kou SC, Chiang JH, Kohane IS, Snyder M.
J Proteome Res
View full abstract on Pubmed
Artificial intelligence in healthcare
Authors: Yu KH, Beam AL, Kohane IS
Nat Biomed Eng
Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma.
Authors: Yu KH, Berry GJ, Rubin DL, Ré C, Altman RB, Snyder M.
Cell Syst
View full abstract on Pubmed
Promoting human rights through science.
Authors: Segal L, Chow RD, Kumar B, Nguyen J, Yu KH, Chen J, Polat EO, Porter KE, Kelly-Irving M, Bimpe I, Winter KA, Zeng R, Ahmed M, Saalman DR, James JI, Kosinski M, White ER, Oda FS, Bretscher H, Hamel P, Negi S, Jawaid A.
Science
View full abstract on Pubmed
Omics AnalySIs System for PRecision Oncology (OASISPRO): A Web-based Omics Analysis Tool for Clinical Phenotype Prediction.
Authors: Yu KH, Fitzpatrick MR, Pappas L, Chan W, Kung J, Snyder M.
Bioinformatics
View full abstract on Pubmed
Artificial intelligence in research.
Authors: Musib M, Wang F, Tarselli MA, Yoho R, Yu KH, Andrés RM, Greenwald NF, Pan X, Lee CH, Zhang J, Dutton-Regester K, Johnston JW, Sharafeldin IM.
Science
View full abstract on Pubmed
Biomedical informatics advancing the national health agenda: the AMIA 2015 year-in-review in clinical and consumer informatics.
Authors: Roberts K, Boland MR, Pruinelli L, Dcruz J, Berry A, Georgsson M, Hazen R, Sarmiento RF, Backonja U, Yu KH, Jiang Y, Brennan PF.
J Am Med Inform Assoc
View full abstract on Pubmed
HARNESSING BIG DATA FOR PRECISION MEDICINE: INFRASTRUCTURES AND APPLICATIONS.
Authors: Yu KH, Hart SN, Goldfeder R, Zhang QC, Parker SCJ, Snyder M.
Pac Symp Biocomput
View full abstract on Pubmed