Paul Avillach

Paul Avillach, MD, PhD

Associate Professor of Biomedical Informatics, Harvard Medical School
Assistant Professor of Pediatrics, Boston Children's Hospital
Assistant Professor in the Department of Epidemiology, Harvard T.H. Chan School of Public Health

10 Shattuck Street, Boston MA 02115

Avillach Lab

Paul Avillach  holds an MD in public health and epidemiology from the University of Bordeaux and a PhD in biomedical informatics from the University of Marseilles. Avillach's research focuses on the development of novel methods and techniques for the integration of multiple heterogeneous clinic cohorts, electronic health records data, and multiple types of genomics data to encompass biological observations. He is PI and Co-Investigator on several large projects at DBMI, including the BD2K PIC-SURE Center of Excellence, the Global Rare Diseases Registry project, the PCORI ARCH project, and the PCORI Phelan-Mcdermid Syndrome project.


DBMI Research Areas
DBMI Courses
Phenome-wide association studies on a quantitative trait: application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics.
Authors: Neuraz A, Chouchana L, Malamut G, Le Beller C, Roche D, Beaune P, Degoulet P, Burgun A, Loriot MA, Avillach P.
PLoS Comput Biol
View full abstract on Pubmed
Gathering and exploring scientific knowledge in pharmacovigilance.
Authors: Lopes P, Nunes T, Campos D, Furlong LI, Bauer-Mehren A, Sanz F, Carrascosa MC, Mestres J, Kors J, Singh B, van Mulligen E, Van der Lei J, Diallo G, Avillach P, Ahlberg E, Boyer S, Diaz C, Oliveira JL.
PLoS One
View full abstract on Pubmed
Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system.
Authors: Coloma PM, Schuemie MJ, Trifirò G, Furlong L, van Mulligen E, Bauer-Mehren A, Avillach P, Kors J, Sanz F, Mestres J, Oliveira JL, Boyer S, Helgee EA, Molokhia M, Matthews J, Prieto-Merino D, Gini R, Herings R, Mazzaglia G, Picelli G, Scotti L, Pedersen L, van der Lei J, Sturkenboom M.
PLoS One
View full abstract on Pubmed
Risk factors and clinical outcome of unsuspected pulmonary embolism in cancer patients: a case-control study.
Authors: Sahut D'Izarn M, Caumont Prim A, Planquette B, Revel MP, Avillach P, Chatellier G, Sanchez O, Meyer G.
J Thromb Haemost
View full abstract on Pubmed
Effect of competition bias in safety signal generation: analysis of a research database of spontaneous reports in France.
Authors: Pariente A, Avillach P, Salvo F, Thiessard F, Miremont-Salamé G, Fourrier-Reglat A, Haramburu F, Bégaud B, Moore N.
Drug Saf
View full abstract on Pubmed
Automatic filtering and substantiation of drug safety signals.
Authors: Bauer-Mehren A, van Mullingen EM, Avillach P, Carrascosa Mdel C, Garcia-Serna R, Piñero J, Singh B, Lopes P, Oliveira JL, Diallo G, Ahlberg Helgee E, Boyer S, Mestres J, Sanz F, Kors JA, Furlong LI.
PLoS Comput Biol
View full abstract on Pubmed
EU-ADR healthcare database network vs. spontaneous reporting system database: preliminary comparison of signal detection.
Authors: Trifirò G, Patadia V, Schuemie MJ, Coloma PM, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Giaquinto C, Scotti L, Pedersen L, Avillach P, Sturkenboom MC, van der Lei J.
Stud Health Technol Inform
View full abstract on Pubmed
A potential competition bias in the detection of safety signals from spontaneous reporting databases.
Authors: Pariente A, Didailler M, Avillach P, Miremont-Salamé G, Fourrier-Reglat A, Haramburu F, Moore N.
Pharmacoepidemiol Drug Saf
View full abstract on Pubmed
Design and evaluation of a semantic approach for the homogeneous identification of events in eight patient databases: a contribution to the European EU-ADR project.
Authors: Avillach P, Joubert M, Thiessard F, Trifirò G, Dufour JC, Pariente A, Mougin F, Polimeni G, Catania MA, Giaquinto C, Mazzaglia G, Fornari C, Herings R, Gini R, Hippisley-Cox J, Molokhia M, Pedersen L, Fourrier-Réglat A, Sturkenboom M, Fieschi M.
Stud Health Technol Inform
View full abstract on Pubmed
A semantic approach for the homogeneous identification of events in eight patient databases: a contribution to the European eu-ADR project.
Authors: Avillach P, Mougin F, Joubert M, Thiessard F, Pariente A, Dufour JC, Trifirò G, Polimeni G, Catania MA, Giaquinto C, Mazzaglia G, Baio G, Herings R, Gini R, Hippisley-Cox J, Molokhia M, Pedersen L, Fourrier-Réglat A, Sturkenboom M, Fieschi M.
Stud Health Technol Inform
View full abstract on Pubmed