Shawn Norman Murphy, M.D., Ph.D.

Shawn Murphy, MD, PhD

Professor of Neurology at MGH
Associate Professor of Biomedical Informatics, Harvard Medical School (Secondary)

6177247980

Shawn Murphy currently serves as the Director of Research Computing and Informatics at Partners Healthcare and Associate Director for the Laboratory of Computer Science at the Massachusetts General Hospital where he developed the Research Patient Data Registry (RPDR) for Partners Healthcare. This application, which serves over 5,000 investigators performing research using the hospital medical record, served as the test bed for his work with Zak Kohane in developing the open source Informatics for Integrating Biology and the Bedside (i2b2) software platform now operating at over 120 hospitals worldwide. Murphy’s contribution as chief architect of the i2b2 platform has served to strengthen the understanding of the metabolic and genetic underpinnings of complex diseases by developing an informatics framework to integrate data for clinical research from electronic health records.

An eMERGE Clinical Center at Partners Personalized Medicine.
Authors: Smoller JW, Karlson EW, Green RC, Kathiresan S, MacArthur DG, Talkowski ME, Murphy SN, Weiss ST.
J Pers Med
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A numerical similarity approach for using retired Current Procedural Terminology (CPT) codes for electronic phenotyping in the Scalable Collaborative Infrastructure for a Learning Health System (SCILHS).
Authors: Klann JG, Phillips LC, Turchin A, Weiler S, Mandl KD, Murphy SN.
BMC Med Inform Decis Mak
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Brain extraction in pediatric ADC maps, toward characterizing neuro-development in multi-platform and multi-institution clinical images.
Authors: Ou Y, Gollub RL, Retzepi K, Reynolds N, Pienaar R, Pieper S, Murphy SN, Grant PE, Zöllei L.
Neuroimage
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Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Authors: Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ.
Inflamm Bowel Dis
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Identification of subjects with polycystic ovary syndrome using electronic health records.
Authors: Castro V, Shen Y, Yu S, Finan S, Pau CT, Gainer V, Keefe CC, Savova G, Murphy SN, Cai T, Welt CK.
Reprod Biol Endocrinol
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Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
Authors: Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T.
J Am Med Inform Assoc
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Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases.
Authors: Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP.
Aliment Pharmacol Ther
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Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.
Authors: Clements CC, Castro VM, Blumenthal SR, Rosenfield HR, Murphy SN, Fava M, Erb JL, Churchill SE, Kaimal AJ, Doyle AE, Robinson EB, Smoller JW, Kohane IS, Perlis RH.
Mol Psychiatry
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Development of phenotype algorithms using electronic medical records and incorporating natural language processing.
Authors: Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I.
BMJ
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Validation of electronic health record phenotyping of bipolar disorder cases and controls.
Authors: Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW.
Am J Psychiatry
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