Shawn Norman Murphy, M.D., Ph.D.

Shawn Murphy, MD, PhD

Professor of Neurology at MGH
Associate Professor of Biomedical Informatics, Harvard Medical School (Secondary)

6177247980

Shawn Murphy currently serves as the Director of Research Computing and Informatics at Partners Healthcare and Associate Director for the Laboratory of Computer Science at the Massachusetts General Hospital where he developed the Research Patient Data Registry (RPDR) for Partners Healthcare. This application, which serves over 5,000 investigators performing research using the hospital medical record, served as the test bed for his work with Zak Kohane in developing the open source Informatics for Integrating Biology and the Bedside (i2b2) software platform now operating at over 120 hospitals worldwide. Murphy’s contribution as chief architect of the i2b2 platform has served to strengthen the understanding of the metabolic and genetic underpinnings of complex diseases by developing an informatics framework to integrate data for clinical research from electronic health records.

Feasibility of Homomorphic Encryption for Sharing I2B2 Aggregate-Level Data in the Cloud.
Authors: Raisaro JL, Klann JG, Wagholikar KB, Estiri H, Hubaux JP, Murphy SN.
AMIA Jt Summits Transl Sci Proc
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i2b2 implemented over SMART-on-FHIR.
Authors: Paris N, Mendis M, Daniel C, Murphy S, Tannier X, Zweigenbaum P.
AMIA Jt Summits Transl Sci Proc
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Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture.
Authors: Can A, Castro VM, Yu S, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Stroke
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Automating Installation of the Integrating Biology and the Bedside (i2b2) Platform.
Authors: Wagholikar KB, Mendis M, Dessai P, Sanz J, Law S, Gilson M, Sanders S, Vangala M, Bell DS, Murphy SN.
Biomed Inform Insights
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Exploring completeness in clinical data research networks with DQe-c.
Authors: Estiri H, Stephens KA, Klann JG, Murphy SN.
J Am Med Inform Assoc
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The Ad-Hoc Uncertainty Principle of Patient Privacy.
Authors: Klann JG, Joss M, Shirali R, Natter M, Schneeweiss S, Mandl KD, Murphy SN.
AMIA Jt Summits Transl Sci Proc
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Biases introduced by filtering electronic health records for patients with "complete data".
Authors: Weber GM, Adams WG, Bernstam EV, Bickel JP, Fox KP, Marsolo K, Raghavan VA, Turchin A, Zhou X, Murphy SN, Mandl KD.
J Am Med Inform Assoc
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Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation.
Authors: Can A, Castro VM, Ozdemir YH, Dagen S, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Dammers R, Weiss ST, Du R.
Neurology
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A Computable Phenotype Improves Cohort Ascertainment in a Pediatric Pulmonary Hypertension Registry.
Authors: Geva A, Gronsbell JL, Cai T, Cai T, Murphy SN, Lyons JC, Heinz MM, Natter MD, Patibandla N, Bickel J, Mullen MP, Mandl KD.
J Pediatr
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Using clinically acquired MRI to construct age-specific ADC atlases: Quantifying spatiotemporal ADC changes from birth to 6-year old.
Authors: Ou Y, Zöllei L, Retzepi K, Castro V, Bates SV, Pieper S, Andriole KP, Murphy SN, Gollub RL, Grant PE.
Hum Brain Mapp
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