Tianxi Cai, ScD
Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)
Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.
DBMI Research Areas
f(1Feature Extraction for Phenotyping from Semantic and Knowledge Resources.
Authors: Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S.
J Biomed Inform
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J Biomed Inform
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Variance components genetic association test for zero-inflated count outcomes.
Use of natural language processing in electronic medical records to identify pregnant women with suicidal behavior: towards a solution to the complex classification problem.
Authors: Zhong QY, Mittal LP, Nathan MD, Brown KM, Knudson González D, Cai T, Finan S, Gelaye B, Avillach P, Smoller JW, Karlson EW, Cai T, Williams MA.
Eur J Epidemiol
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Eur J Epidemiol
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Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes.
Authors: Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T.
Sci Data
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Sci Data
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Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.
Authors: Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH.
Semin Arthritis Rheum
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Semin Arthritis Rheum
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Distinct Proteomic Signatures in 16 HDL (High-Density Lipoprotein) Subspecies.
Authors: Furtado JD, Yamamoto R, Melchior JT, Andraski AB, Gamez-Guerrero M, Mulcahy P, He Z, Cai T, Davidson WS, Sacks FM.
Arterioscler Thromb Vasc Biol
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Arterioscler Thromb Vasc Biol
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Semi-supervised Validation of Multiple Surrogate Outcomes with Application to Electronic Medical Records Phenotyping.
Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study.
Authors: Can A, Rudy RF, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Neurology
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Neurology
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Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.
Authors: Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Stroke
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Stroke
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FUNCTIONAL PRINCIPAL VARIANCE COMPONENT TESTING FOR A GENETIC ASSOCIATION STUDY OF HIV PROGRESSION.