Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

617-432-4923
CELEHS

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Semi-supervised estimation of covariance with application to phenome-wide association studies with electronic medical records data.
Authors: Chan SF, Hejblum BP, Chakrabortty A, Cai T.
Stat Methods Med Res
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Large-Scale Simultaneous Testing of Cross-Covariance Matrices with Applications to PheWAS.
Authors: Cai T, Cai TT, Liao K, Liu W.
Stat Sin
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Associations of antepartum suicidal behaviour with adverse infant and obstetric outcomes.
Authors: Zhong QY, Gelaye B, Karlson EW, Avillach P, Smoller JW, Cai T, Williams MA.
Paediatr Perinat Epidemiol
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Automated feature selection of predictors in electronic medical records data.
Authors: Gronsbell J, Minnier J, Yu S, Liao K, Cai T.
Biometrics
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f(1Feature Extraction for Phenotyping from Semantic and Knowledge Resources.
Authors: Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S.
J Biomed Inform
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Use of natural language processing in electronic medical records to identify pregnant women with suicidal behavior: towards a solution to the complex classification problem.
Authors: Zhong QY, Mittal LP, Nathan MD, Brown KM, Knudson González D, Cai T, Finan S, Gelaye B, Avillach P, Smoller JW, Karlson EW, Cai T, Williams MA.
Eur J Epidemiol
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Variance components genetic association test for zero-inflated count outcomes.
Authors: Goodman MO, Chibnik L, Cai T.
Genet Epidemiol
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Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes.
Authors: Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T.
Sci Data
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Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.
Authors: Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH.
Semin Arthritis Rheum
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Distinct Proteomic Signatures in 16 HDL (High-Density Lipoprotein) Subspecies.
Authors: Furtado JD, Yamamoto R, Melchior JT, Andraski AB, Gamez-Guerrero M, Mulcahy P, He Z, Cai T, Davidson WS, Sacks FM.
Arterioscler Thromb Vasc Biol
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