Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

617-432-4923
CELEHS

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Retrospective likelihood-based methods for analyzing case-cohort genetic association studies.
Authors: Shen Y, Cai T, Chen Y, Yang Y, Chen J.
Biometrics
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Assessing incremental value of biomarkers with multi-phase nested case-control studies.
Authors: Zhou QM, Zheng Y, Chibnik LB, Karlson EW, Cai T.
Biometrics
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Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Authors: Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ.
Inflamm Bowel Dis
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Identification of subjects with polycystic ovary syndrome using electronic health records.
Authors: Castro V, Shen Y, Yu S, Finan S, Pau CT, Gainer V, Keefe CC, Savova G, Murphy SN, Cai T, Welt CK.
Reprod Biol Endocrinol
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Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
Authors: Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T.
J Am Med Inform Assoc
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Alternatives to Hazard Ratios for Comparing the Efficacy or Safety of Therapies in Noninferiority Studies.
Authors: Uno H, Wittes J, Fu H, Solomon SD, Claggett B, Tian L, Cai T, Pfeffer MA, Evans SR, Wei LJ.
Ann Intern Med
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Testing Differential Networks with Applications to Detecting Gene-by-Gene Interactions.
Authors: Xia Y, Cai T, Cai TT.
Biometrika
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Development of phenotype algorithms using electronic medical records and incorporating natural language processing.
Authors: Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I.
BMJ
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Risk Classification with an Adaptive Naive Bayes Kernel Machine Model.
Authors: Minnier J, Yuan M, Liu JS, Cai T.
J Am Stat Assoc
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Validation of electronic health record phenotyping of bipolar disorder cases and controls.
Authors: Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW.
Am J Psychiatry
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