Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach.
Authors: Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP.
Inflamm Bowel Dis
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Six articles related to risk assessment and prediction based on work presented at the October 12–14, 2011 Conference on Risk Assessment and Evaluation of Predictions in Silver Spring, Maryland.
Authors: Gail MH, Pfeiffer RM, Cai T.
Lifetime Data Anal
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Subgroup specific incremental value of new markers for risk prediction.
Authors: Zhou QM, Zheng Y, Cai T.
Lifetime Data Anal
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Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis.
Authors: Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP.
Am J Gastroenterol
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Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.
Authors: Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM.
Arthritis Rheum
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Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease.
Authors: Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP.
Aliment Pharmacol Ther
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EFFECTIVELY SELECTING A TARGET POPULATION FOR A FUTURE COMPARATIVE STUDY.
Authors: Zhao L, Tian L, Cai T, Claggett B, Wei LJ.
J Am Stat Assoc
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Resampling Procedures for Making Inference under Nested Case-control Studies.
Authors: Cai T, Zheng Y.
J Am Stat Assoc
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Pathprinting: An integrative approach to understand the functional basis of disease.
Authors: Altschuler GM, Hofmann O, Kalatskaya I, Payne R, Ho Sui SJ, Saxena U, Krivtsov AV, Armstrong SA, Cai T, Stein L, Hide WA.
Genome Med
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Modeling disease severity in multiple sclerosis using electronic health records.
Authors: Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL.
PLoS One
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