Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Comparing costs associated with risk stratification rules for t-year survival.
Authors: Cai T, Tian L, Lloyd-Jones DM.
Biostatistics
View full abstract on Pubmed
Kernel machine approach to testing the significance of multiple genetic markers for risk prediction.
Authors: Cai T, Tonini G, Lin X.
Biometrics
View full abstract on Pubmed
Rare-variant association testing for sequencing data with the sequence kernel association test.
Authors: Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X.
Am J Hum Genet
View full abstract on Pubmed
Robust prediction of t-year survival with data from multiple studies.
Authors: Cai T, Gerds TA, Zheng Y, Chen J.
Biometrics
View full abstract on Pubmed
The highest confidence density region and its usage for joint inferences about constrained parameters.
Authors: Tian L, Wang R, Cai T, Wei LJ.
Biometrics
View full abstract on Pubmed
On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data.
Authors: Uno H, Cai T, Pencina MJ, D'Agostino RB, Wei LJ.
Stat Med
View full abstract on Pubmed
Analysis of randomized comparative clinical trial data for personalized treatment selections.
Authors: Cai T, Tian L, Wong PH, Wei LJ.
Biostatistics
View full abstract on Pubmed
Validation of psoriatic arthritis diagnoses in electronic medical records using natural language processing.
Authors: Love TJ, Cai T, Karlson EW.
Semin Arthritis Rheum
View full abstract on Pubmed
Incorporating short-term outcome information to predict long-term survival with discrete markers.
Authors: Parast L, Cheng SC, Cai T.
Biom J
View full abstract on Pubmed
Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.
Authors: Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, Raychaudhuri S, Kohane I, Karlson E, Plenge RM.
Am J Hum Genet
View full abstract on Pubmed