Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

617-432-4923
CELEHS

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Temporal bias in case-control design: preventing reliable predictions of the future.
Authors: Yuan W, Beaulieu-Jones BK, Yu KH, Lipnick SL, Palmer N, Loscalzo J, Cai T, Kohane IS.
Nat Commun
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International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study.
Authors: Weber GM, Hong C, Palmer NP, Avillach P, Murphy SN, Gutiérrez-Sacristán A, Xia Z, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, Beaulieu-Jones BK, Bellazzi R, Agapito G, Alessiani M, Aronow BJ, Bell DS, Bellasi A, Benoit V, Beraghi M, Boeker M, Booth J, Bosari S, Bourgeois FT, Brown NW, Bucalo M, Chiovato L, Chiudinelli L, Dagliati A, Devkota B, DuVall SL, Follett RW, Ganslandt T, García Barrio N, Gradinger T, Griffier R, Hanauer DA, Holmes JH, Horki P, Huling KM, Issitt RW, Jouhet V, Keller MS, Kraska D, Liu M, Luo Y, Lynch KE, Malovini A, Mandl KD, Mao C, Maram A, Matheny ME, Maulhardt T, Mazzitelli M, Milano M, Moore JH, Morris JS, Morris M, Mowery DL, Naughton TP, Ngiam KY, Norman JB, Patel LP, Pedrera Jimenez M, Ramoni RB, Schriver ER, Scudeller L, Sebire NJ, Serrano Balazote P, Spiridou A, Tan AL, Tan BW, Tibollo V, Torti C, Trecarichi EM, Vitacca M, Zambelli A, Zucco C, Kohane IS, Cai T, Brat GA.
medRxiv
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Vascular Geometry Associated with Anterior Communicating Artery Aneurysm Formation.
Authors: Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R.
World Neurosurg
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Multinational Prevalence of Neurological Phenotypes in Patients Hospitalized with COVID-19.
Authors: Le TT, Gutiérrez-Sacristán A, Son J, Hong C, South AM, Beaulieu-Jones BK, Loh NHW, Luo Y, Morris M, Ngiam KY, Patel LP, Samayamuthu MJ, Schriver E, Tan AL, Moore J, Cai T, Omenn GS, Avillach P, Kohane IS, Visweswaran S, Mowery DL, Xia Z.
medRxiv
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Morphological variables associated with ruptured basilar tip aneurysms.
Authors: Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R.
Sci Rep
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EFFICIENT AND ROBUST ESTIMATION OF t-YEAR RISK PREDICTION MODELS LEVERAGING TIME VARYING INTERMEDIATE OUTCOMES.
Authors: Zheng Y, Lu T, Cai T.
Stat Sin
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Protein-Defined Subspecies of HDLs (High-Density Lipoproteins) and Differential Risk of Coronary Heart Disease in 4 Prospective Studies.
Authors: Sacks FM, Liang L, Furtado JD, Cai T, Davidson WS, He Z, McClelland RL, Rimm EB, Jensen MK.
Arterioscler Thromb Vasc Biol
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Phenome-wide examination of comorbidity burden and multiple sclerosis disease severity.
Authors: Zhang T, Goodman M, Zhu F, Healy B, Carruthers R, Chitnis T, Weiner H, Cai T, De Jager P, Tremlett H, Xia Z.
Neurol Neuroimmunol Neuroinflamm
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Surrounding vascular geometry associated with basilar tip aneurysm formation.
Authors: Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R.
Sci Rep
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Evaluating multiple surrogate markers with censored data.
Authors: Parast L, Cai T, Tian L.
Biometrics
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