Nils Gehlenborg

Nils Gehlenborg, PhD

Associate Professor of Biomedical Informatics
Director, Master of Biomedical Informatics (MBI) Program

10 Shattuck Street, Boston, MA 02115

Nils Gehlenborg  received his PhD from the University of Cambridge and was a predoctoral fellow at the European Bioinformatics Institute (EMBL-EBI).

The goal of Gehlenborg’s research is to improve human health by developing computational techniques and interfaces that enable scientists and clinicians to efficiently interact with biomedical data. Tight integration of algorithmic approaches from biomedical informatics with advanced data visualization techniques is central to his efforts, as is close collaboration with clinicians and experimentalists. Currently, Gehlenborg is researching and developing novel tools to visualize heterogeneous data from large-scale cancer genomics studies such as The Cancer Genome Atlas, integrating visual and computational approaches to support sense-making in biology, and using software to support reproducible collaborative research in epigenomics and genomics.

Gehlenborg is a co-founder and former general chair of BioVis, the Symposium on Biological Data Visualization, and co-founder of VIZBI, the annual workshop on Visualizing Biological Data. Occasionally, he contributes to the “Points of View” data visualization column in Nature Methods.

Gehlenborg currently serves as the Director of the Master of Biomedical Informatics (MBI) program at Harvard Medical School.


DBMI Research Areas
DBMI Courses
UpSet: Visualization of Intersecting Sets.
Authors: Lex A, Gehlenborg N, Strobelt H, Vuillemot R, Pfister H.
IEEE Trans Vis Comput Graph
View full abstract on Pubmed
Domino: Extracting, Comparing, and Manipulating Subsets Across Multiple Tabular Datasets.
Authors: Gratzl S, Gehlenborg N, Lex A, Pfister H, Streit M.
IEEE Trans Vis Comput Graph
View full abstract on Pubmed
Characterization of HPV and host genome interactions in primary head and neck cancers.
Authors: Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, Ren X, Zhang J, Pantazi A, Santoso N, Xu AW, Mahadeshwar H, Wheeler DA, Haddad RI, Jung J, Ojesina AI, Issaeva N, Yarbrough WG, Hayes DN, Grandis JR, El-Naggar AK, Meyerson M, Park PJ, Chin L, Seidman JG, Hammerman PS, Kucherlapati R.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Guided visual exploration of genomic stratifications in cancer.
Authors: Streit M, Lex A, Gratzl S, Partl C, Schmalstieg D, Pfister H, Park PJ, Gehlenborg N.
Nat Methods
View full abstract on Pubmed
Comparative analysis of metazoan chromatin organization.
Authors: Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Chen RA, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Liu XS, Lieb JD, Ahringer J, Karpen GH, Park PJ.
Nature
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Bar charts and box plots.
Authors: Streit M, Gehlenborg N.
Nat Methods
View full abstract on Pubmed
LineUp: visual analysis of multi-attribute rankings.
Authors: Gratzl S, Lex A, Gehlenborg N, Pfister H, Streit M.
IEEE Trans Vis Comput Graph
View full abstract on Pubmed
The Cancer Genome Atlas Pan-Cancer analysis project.
Authors: Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM.
Nat Genet
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Comprehensive molecular characterization of clear cell renal cell carcinoma.

Nature
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Diverse mechanisms of somatic structural variations in human cancer genomes.
Authors: Yang L, Luquette LJ, Gehlenborg N, Xi R, Haseley PS, Hsieh CH, Zhang C, Ren X, Protopopov A, Chin L, Kucherlapati R, Lee C, Park PJ.
Cell
View full abstract on Pubmed