Shawn Norman Murphy, M.D., Ph.D.

Shawn Murphy, MD, PhD

Professor of Neurology at MGH
Associate Professor of Biomedical Informatics, Harvard Medical School (Secondary)

6177247980

Shawn Murphy currently serves as the Director of Research Computing and Informatics at Partners Healthcare and Associate Director for the Laboratory of Computer Science at the Massachusetts General Hospital where he developed the Research Patient Data Registry (RPDR) for Partners Healthcare. This application, which serves over 5,000 investigators performing research using the hospital medical record, served as the test bed for his work with Zak Kohane in developing the open source Informatics for Integrating Biology and the Bedside (i2b2) software platform now operating at over 120 hospitals worldwide. Murphy’s contribution as chief architect of the i2b2 platform has served to strengthen the understanding of the metabolic and genetic underpinnings of complex diseases by developing an informatics framework to integrate data for clinical research from electronic health records.

Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.
Authors: Tatonetti NP, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, Yue P, Tsao PS, Tsau PS, Kohane I, Roden DM, Altman RB.
Clin Pharmacol Ther
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Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.
Authors: Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, Raychaudhuri S, Kohane I, Karlson E, Plenge RM.
Am J Hum Genet
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Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2).
Authors: Murphy SN, Weber G, Mendis M, Gainer V, Chueh HC, Churchill S, Kohane I.
J Am Med Inform Assoc
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I am Not Dead Yet: Identification of False-Positive Matches to Death Master File.
Authors: Turchin A, Shubina M, Murphy SN.
AMIA Annu Symp Proc
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Electronic medical records for discovery research in rheumatoid arthritis.
Authors: Liao KP, Cai T, Gainer V, Goryachev S, Zeng-treitler Q, Raychaudhuri S, Szolovits P, Churchill S, Murphy S, Kohane I, Karlson EW, Plenge RM.
Arthritis Care Res (Hoboken)
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Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records.
Authors: Brownstein JS, Murphy SN, Goldfine AB, Grant RW, Sordo M, Gainer V, Colecchi JA, Dubey A, Nathan DM, Glaser JP, Kohane IS.
Diabetes Care
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The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.
Authors: Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill S, Kohane IS.
J Am Med Inform Assoc
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Instrumenting the health care enterprise for discovery research in the genomic era.
Authors: Murphy S, Churchill S, Bry L, Chueh H, Weiss S, Lazarus R, Zeng Q, Dubey A, Gainer V, Mendis M, Glaser J, Kohane I.
Genome Res
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A PSO/ACO approach to knowledge discovery in a pharmacovigilance context
Authors: Sordo, M., Ochoa, G., Murphy, S.N
Genetic and Evolutionary Computation Conference - GECCO
E-facts: business process management in clinical data repositories.
Authors: Wattanasin N, Peng Z, Raine C, Mitchell M, Wang C, Murphy SN.
AMIA Annu Symp Proc
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