Tianxi Cai, ScD
Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)
Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.
DBMI Research Areas
Robust risk prediction with biomarkers under two-phase stratified cohort design.
Identifying predictive markers for personalized treatment selection.
Inference for survival prediction under the regularized Cox model.
A predictive enrichment procedure to identify potential responders to a new therapy for randomized, comparative controlled clinical studies.
Authors: Li J, Zhao L, Tian L, Cai T, Claggett B, Callegaro A, Dizier B, Spiessens B, Ulloa-Montoya F, Wei LJ.
Biometrics
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Biometrics
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Integrative genomic testing of cancer survival using semiparametric linear transformation models.
Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases.
Authors: Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I.
Clin Gastroenterol Hepatol
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Clin Gastroenterol Hepatol
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Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers.
Authors: Stein MB, Chen CY, Ursano RJ, Cai T, Gelernter J, Heeringa SG, Jain S, Jensen KP, Maihofer AX, Mitchell C, Nievergelt CM, Nock MK, Neale BM, Polimanti R, Ripke S, Sun X, Thomas ML, Wang Q, Ware EB, Borja S, Kessler RC, Smoller JW.
JAMA Psychiatry
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JAMA Psychiatry
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Kernel machine testing for risk prediction with stratified case cohort studies.
Suicidal behavior-related hospitalizations among pregnant women in the USA, 2006-2012.
Authors: Zhong QY, Gelaye B, Miller M, Fricchione GL, Cai T, Johnson PA, Henderson DC, Williams MA.
Arch Womens Ment Health
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Arch Womens Ment Health
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Mediation analysis for survival data using semiparametric probit models.
