Tianx Cai

Tianxi Cai, ScD

Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

10 Shattuck Street, Room 434, Boston, MA 02115

617-432-4923
CELEHS

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
High-throughput multimodal automated phenotyping (MAP) with application to PheWAS.
Authors: Liao KP, Sun J, Cai TA, Link N, Hong C, Huang J, Huffman JE, Gronsbell J, Zhang Y, Ho YL, Castro V, Gainer V, Murphy SN, O'Donnell CJ, Gaziano JM, Cho K, Szolovits P, Kohane IS, Yu S, Cai T.
J Am Med Inform Assoc
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A fast divide-and-conquer sparse Cox regression.
Authors: Wang Y, Hong C, Palmer N, Di Q, Schwartz J, Kohane I, Cai T.
Biostatistics
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Use of Narrative Concepts in Electronic Health Records to Validate Associations Between Genetic Factors and Response to Treatment of Inflammatory Bowel Diseases.
Authors: Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Savova G, Shaw SY, Churchill S, Burke KE, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ.
Clin Gastroenterol Hepatol
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Using a surrogate marker for early testing of a treatment effect.
Authors: Parast L, Cai T, Tian L.
Biometrics
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Decreased Total Iron Binding Capacity May Correlate with Ruptured Intracranial Aneurysms.
Authors: Can A, Lai PMR, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Sci Rep
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Assessing the value of a censored surrogate outcome.
Authors: Parast L, Tian L, Cai T.
Lifetime Data Anal
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Semi-supervised estimation of covariance with application to phenome-wide association studies with electronic medical records data.
Authors: Chan SF, Hejblum BP, Chakrabortty A, Cai T.
Stat Methods Med Res
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Large-Scale Simultaneous Testing of Cross-Covariance Matrices with Applications to PheWAS.
Authors: Cai T, Cai TT, Liao K, Liu W.
Stat Sin
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Associations of antepartum suicidal behaviour with adverse infant and obstetric outcomes.
Authors: Zhong QY, Gelaye B, Karlson EW, Avillach P, Smoller JW, Cai T, Williams MA.
Paediatr Perinat Epidemiol
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Automated feature selection of predictors in electronic medical records data.
Authors: Gronsbell J, Minnier J, Yu S, Liao K, Cai T.
Biometrics
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